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A Novel In Vitro Model of the Bone Marrow Microenvironment in Acute Myeloid Leukemia Identifies CD44 and Focal Adhesion Kinase as Therapeutic Targets to Reverse Cell Adhesion-Mediated Drug Resistance
Background/Objectives: Acute myeloid leukemia (AML) is an aggressive neoplasm. Although most patients respond to induction therapy, …
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The NF-κB multidimer system model: A knowledge base to explore diverse biological contexts
The nuclear factor κB (NF-κB) system is critical for various biological functions in numerous cell types, including the inflammatory …
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The NF-κB multidimer system model: A knowledge base to explore diverse biological contexts
Dissecting the Impact of Bromodomain Inhibitors on the IRF4-MYC Oncogenic Axis in Multiple Myeloma
B-cell progenitor fate determinant interferon regulatory factor 4 (IRF4) exerts key roles in the pathogenesis and progression of …
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Dissecting the Impact of Bromodomain Inhibitors on the IRF4-MYC Oncogenic Axis in Multiple Myeloma
Elucidation of Focal Adhesion Kinase as a Modulator of Migration and Invasion and as a Potential Therapeutic Target in Chronic Lymphocytic Leukemia
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Targeting the non-canonical NF-κB pathway in chronic lymphocytic leukemia and multiple myeloma
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