Mitchell Lab
Mitchell Lab
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Alexander Hoffmann
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The NF-κB multidimer system model: A knowledge base to explore diverse biological contexts
An incoherent feedforward loop interprets NF$ąppa$B/RelA dynamics to determine TNF-induced necroptosis decisions
A regulatory circuit controlling the dynamics of NFκB cRel transitions B cells from proliferation to plasma cell differentiation
An NFκB activity calculator to delineate signaling crosstalk: type I and II interferons enhance NFκB via distinct mechanisms
Substrate complex competition is a regulatory motif that allows NFκB RelA to license but not amplify NFκB RelB
Deriving Quantitative Cell Biological Information from Dye-Dilution Lymphocyte Proliferation Experiments
Identifying noise sources governing cell-to-cell variability
Nongenetic origins of cell-to-cell variability in B lymphocyte proliferation
Polypyrimidine tract-binding protein blocks miRNA-124 biogenesis to enforce its neuronal-specific expression in the mouse
Signaling via the NF$ąppa$B system
Studying NF-$ąppa$B signaling with mathematical models
Training the 21st century immunologist
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